A stunning oceanfront mansion tied to renowned cancer philanthropists is now listed for $25.5 million—potentially setting a new sales record in Ponte Vedra Beach.

If sold at asking price, the 10-bedroom, 9,870-square-foot estate at 1185 Ponte Vedra Boulevard would surpass the previous record of $22 million, set when former T-Mobile CEO John Legere purchased a nearby property in January.

Key Details:

• Seller: The Sontag Foundation, a leading brain tumor research nonprofit.
• Owners: Founded by Susan and Rick Sontag after Susan’s 1994 brain cancer diagnosis.
• Broker: Michelle Floyd of ONE Sotheby’s International.
• History: Rick Sontag, a Harvard Business School graduate, sold his aerospace firm, Unison Industries, in 2002 and used the proceeds to fund cancer research.

The nearly 3-acre estate was previously listed with two additional lots, but the updated listing now focuses solely on the mansion.